Bir üremeye yardımcı tedaviler merkezine 2006 yılında başvuran infertil erkeklerde bazı risk etmenleri

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2008

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Sağlık Bilimleri Enstitüsü

Abstract

Infertility is, by definition, the inability to conceive after 1 year of unprotected sexual intercourse. This could indicate malfunctioning of the natural conception mechanisms. The problems could be due to either a male or a female factor, or in some cases both. The contribution of occupational influences to infertility is a much discussed subject.In this study, the relationship between occupation and infertility has been investigated in males and the extent of the relationship has been evaluated. The study case (n=86) consisted of the male partners of couples who were unable to conceive after 12 months and where the infertility was due to the male factor and for whom there was no known medical condition that could account for their infertility. The control group (n=110) composed of fertile men of couples where the female partners have been determined as the factor for their inability to conceive.Both groups answered a questionnaire and were subjected to semen analysis. The following occupations were grouped together and considered as sedentary workers: banker, engineer, merchant, driver, manager, tailor, musician, architects, accountant, academic, religious worker, lawyer. The following were grouped as non-sedentary workers: soldier, teacher, salesman, health-related workers, doctor, construction manager, technician, policeman, shop assistant. The following was considered as heavy workers group: farmer, furniture makers & carpenters, unqualified worker, cleaner, foreman, machine operator, and cook.The results showed both complementary and conflicting findings compared with the literature. According to financial status, a significant difference was observed between case and control groups (p=0.026), with most of the control group being in the upper level in earnings. A significant difference was also observed between groups (p=0.017) related to smokers and within the control group there is a higher number of smokers. In the sedentary group of workers, we have observed below normal sperm morphology in the case group compared with the control group. In the case group non-sedentary workers showed a lower sperm count. In heavy workers group, sperm count, mobility and normal sperm morphology were lower in the case group.The literature shows conflicting results in male infertility studies, however, there is a common consensus that male infertility is multi-factorial and could result from prenatal and development after birth, education, food habits, lifestyle factors, smoking and occupational risks. To determine the real factors, large multi-centered epidemiological studies are needed. Our study can be considered as a preliminary investigation that contributes to the limited number of studies in the literature on male infertility.

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