Cilt:28 Sayı:02 (2019)

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Synthesıs of open-chaın sugar derıvatıves as antıcancer and antımıcrobıal agents
(Ankara Üniversitesi Fen Fakültesi, 2019) Yazgan, İdris; Other; Other
In the present study, three sugar residues including mannose, galactose and lactose were modified with organic substituents via reductive amination reaction in order to get strong anticancer carbohydrate derivatives for A549 cell line and antibacterial agents targeting E.coli and S.epidermidis. The findings showed that carbohydrate residue along with substituted group play the major role for the observed activity of the carbohydrate ligands.