Synthesıs of open-chaın sugar derıvatıves as antıcancer and antımıcrobıal agents
No Thumbnail Available
Date
2019
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Ankara Üniversitesi Fen Fakültesi
Abstract
In the present study, three sugar residues including mannose, galactose and lactose were modified with organic substituents via reductive amination reaction in order to get strong anticancer carbohydrate derivatives for A549 cell line and antibacterial agents targeting E.coli and S.epidermidis. The findings showed that carbohydrate residue along with substituted group play the major role for the observed activity of the carbohydrate ligands.
Description
Keywords
Carbohydrate derivatives, Anticancer, Antibacteri