Insulin-like growth factor-1 gene expression in the endometrium of repeat breeder cows after the administration of presynch-10 and ovsynch protocol

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dc.contributor.authorAğaoğlu, Ali Reha
dc.contributor.authorAğaoğlu, Özgecan Korkmaz
dc.contributor.authorSidekli, Özge
dc.contributor.authorKocamüftüoğlu, Mesih
dc.contributor.departmentVeteriner Fakültesitr_TR
dc.date.accessioned2021-10-07T14:04:35Z
dc.date.available2021-10-07T14:04:35Z
dc.date.issued2020-03-03
dc.description.abstractThe aim of this study was to investigate the effects of using presynch-10 and ovsynch synchronization protocols on endometrial expression and serum levels of insulin-like growth factor-1 (IGF-1) that thought to play roles during endometrial healing process in cows diagnosed with repeat breeder syndrome (RBS) and subclinical endometritis (SE). A total of 40 Holstein-Friesian cows identified as having RBS and SE were used. The animals in Group 1 (G1, n=20) were applied presynch-10 and ovsynch furthermore, biopsy and blood samples were collected both before and after administration. Biopsy and blood samples were taken from the animals in Group 2 (G2, n=20) without performing any synchronization. The IGF-1 gene expression profiles were determined in all samples using RT-qPCR. Even though the level of IGF-1 expression increased in samples taken after synchronization in G1, it was not statistically significant (P>0.05). There was no statistical difference in serum IGF-1 levels between G1 and G2 (P>0.05). In conclusion, the expression of the IGF-1 gene in the endometrial tissue of RBS cows with SE was identified, but the evidence suggests that the synchronization protocols in question had no significant effect on the gene expression profile being investigated.tr_TR
dc.identifier.endpage199tr_TR
dc.identifier.issn/e-issn1308-2817
dc.identifier.issue2tr_TR
dc.identifier.startpage193tr_TR
dc.identifier.urihttps://doi.org/10.33988/auvfd.640288tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/75325
dc.identifier.volume67tr_TR
dc.language.isoentr_TR
dc.publisherAnkara Üniversitesitr_TR
dc.relation.isversionof10.33988/auvfd.640288tr_TR
dc.relation.journalAnkara Üniversitesi Veteriner Fakültesi Dergisitr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectGene expressiontr_TR
dc.subjectIGF-1tr_TR
dc.subjectOvsynchtr_TR
dc.titleInsulin-like growth factor-1 gene expression in the endometrium of repeat breeder cows after the administration of presynch-10 and ovsynch protocoltr_TR
dc.typeArticletr_TR

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Cilt:67 Sayı:02 (2020)