Bazı shiff bazlarının antimikrobiyal aktiviteleri

Abstract

ANTIMICROBIAL ACTIVITIES OF SOME SCHIFF BASESAysun AYDINLI ESENAnkara UniversityGraduate School of Natural and Applied ScienceDepartment of BiologySupervisor: Prof.Dr. Cumhur ÇÖKMÜŞIn this study, the antibacterial activities of 18 newly synthesized Schiff bases examinedon the bacteria Staphylococcus aureus, Enterococcus faecalis, EnterococcusBacillus subtilis, Pseudomonas aeruginosa by diskgallinarum, Esherichia coli,diffusion method.The 6 of 18 Schiff bases, which contain sulfur, ((1-{[(2-mercaptophenyl) imino]methyl}-2-naphtol (SB1), 2-{[(2-mercaptophenyl) imino] methyl] phenol (SB2), 2-[(E)-(4,5-dihydro-1,3-thiazol-2-ylimino) methyl] phenol (SB3), 2-[(1,3-benzothiazol-2-ylimino)methyl] phenol (SB4), 4-chloro-2-[(1,3-thiazol-2-ylimino)mehyl] phenol(SB5), 2-[(1,3-benzothiazol-2-ylimino) methyl]-4-chlorophenyl SB6)) showedantibacterial activity against the bacteria given above. It was determined that the Schiffbase 2-{[(2-mercaptophenyl) imino] methyl] phenol (SH2) showed the highestantibacterial activity against bacteria except E. faecalis.2006, 45 pagesKey Words : Antimicrobial activity, Schiff basesii