Histological study of a corrective influence of a compound potassium 2-((4-amino-5-(morpholinomethyl)- 4h-1,2,4-triazol-3-yl)thio)acetate (pkr-173) on the state of chicken's liver under infection by pseudomonas aeruginosa

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dc.contributor.authorVashchyk, Yevgenia
dc.contributor.authorShcherbyna, Roman
dc.contributor.authorParchenko, Volodymyr
dc.contributor.authorBushueva, Inna
dc.contributor.authorGutyj, Bogdan
dc.contributor.authorFotina, Hanna
dc.contributor.authorFotina, Tatiana
dc.contributor.authorStronskyi, Yuriy
dc.contributor.departmentEczacılık Fakültesitr_TR
dc.date.accessioned2020-04-25T10:20:09Z
dc.date.available2020-04-25T10:20:09Z
dc.date.issued2020
dc.description.abstractotassium 2((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3yl)thio)acetate (PKR-173) with different antibiotics on the state of chicken's liver under infection by Pseudomonas aeruginosa. Material and Method: The histological study was carried out on the levers of intact chickens (intact control); chickens that were infected by the strain of Pseudomonas aeruginosa (controlled pathology); chickens that had (before being infected by Pseudomonas aeruginosa) preventive input of the compound PKR-173 with the classic antibiotic Enrofloxacin or with Saroflox (undergoing research); or were input Thiotriazolin with the classic antibiotic Enrofloxacin. Result and Discussion: As a result, it is stated, that preventive input of the compound PKR-173 with reseachable antibiotic Saroflox, as well as with classic antibiotic Enrofloxacin and Thiotriazolin with antibiotic Enrofloxacin, to chickens infected with pseudomonas aeruginosa, prevents from chickens' livers developing stereotypical morphological changes characteristic of nonspecific reactive hepatitis. Analysis of quantitative characteristics of pathological process that developed in chicken's liver infected with pseudomonas aeruginosa, and the corrective influence of researched methods showed that the compound PKR-173 with antibiotic Saroflox believably lowers displays of all signs of pathology compared to the controlled pathologytr_TR
dc.identifier.endpage17tr_TR
dc.identifier.issn/e-issn1015-3918
dc.identifier.issue01tr_TR
dc.identifier.startpage01tr_TR
dc.identifier.urihttps://doi.org/10.33483/jfpau.567757tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/71145
dc.identifier.volume44tr_TR
dc.language.isoentr_TR
dc.publisherAnkara Üniversitesitr_TR
dc.relation.isversionof10.33483/jfpau.567757tr_TR
dc.relation.journalAnkara Üniversitesi Eczacılık Fakültesi Dergisitr_TR
dc.relation.publicationcategoryMakale - Ulusal - Editör Denetimli Dergi - Başka Kurum Yazarıtr_TR
dc.subjectHepatitistr_TR
dc.subjectHepatoprotective effecttr_TR
dc.subjectInfection of pseudomonastr_TR
dc.subjectSarofloxtr_TR
dc.titleHistological study of a corrective influence of a compound potassium 2-((4-amino-5-(morpholinomethyl)- 4h-1,2,4-triazol-3-yl)thio)acetate (pkr-173) on the state of chicken's liver under infection by pseudomonas aeruginosatr_TR
dc.title.alternativePseudomonas aerugınosa ile enfekte edilmiş civcivlerin karaciğerine potasyum 2-((4-amino-5-(morfolinometil)-4h-1,2,4-triazol-3- il)tiyo)asetat (pkr-173) bileşiğinin düzeltici etkisinin histolojik olarak araştırılmasıtr_TR
dc.typeArticletr_TR

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