Hemostatic Efficacy of Ankaferd Blood Stopper (R) in a Swine Bleeding Model

dc.contributor.authorBilgili, Hasan
dc.contributor.authorCaptug, Ozge
dc.contributor.departmentVETERİNERLİK FAKÜLTESİtr_TR
dc.date.accessioned2019-07-01T12:08:39Z
dc.date.available2019-07-01T12:08:39Z
dc.date.issued2009
dc.description.abstractObjective: The purpose of this study was to show the hemostatic effect of spray, solution and tampon forms of Ankaferd Blood Stopper (R) (ABS), a unique medicinal plant extract historically used as a hemostatic agent in Turkish folklore medicine, in a porcine bleeding model. Materials and Methods: Two 1-year-old pigs were used as bleeding models for superficial and deep skin lacerations, grade II liver and spleen injuries, grade II saphenous vein injury and grade IV saphenous artery injury. Spray, solution or tampon forms of ABS were applied after continuing bleeding was confirmed. The primary outcome was time to hemostasis. Volume of blood loss was not measured. The pigs were euthanized at the end of the experiment. Results: Spray or direct application of ABS solution resulted in instant control of bleeding in superficial and deep skin lacerations as well as puncture wounds of the liver. A 40-second application of ABS tampon was sufficient to stop bleeding of skin lacerations, while 1.5- and 3.5-min applications were used to control hemorrhage from the saphenous vein and artery, respectively. No rebleeding was observed once hemostasis was achieved. However, repeated applications of ABS solution and tampon were only temporarily effective in the hemostasis of spleen injury. Conclusions: The data showed that ABS was an effective hemostatic agent for superficial and deep skin lacerations and minor/moderate trauma injuries in a porcine bleeding model. Copyright (C) 2009 S. Karger AG, Baseltr_TR
dc.description.indexWos
dc.description.indexwos
dc.identifier.endpage05tr_TR
dc.identifier.other10.1159/000204344
dc.identifier.startpage01tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/67074
dc.language.isoentr_TR
dc.relation.journalMEDICAL PRINCIPLES AND PRACTICEtr_TR
dc.subjectHemorrhagetr_TR
dc.subjectPorcine animal modeltr_TR
dc.titleHemostatic Efficacy of Ankaferd Blood Stopper (R) in a Swine Bleeding Modeltr_TR
dc.typeArticletr_TR

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