Pharmaceutical applications based on next generation sequencing technology in oncologic drug development

Simple item page
dc.contributor.authorDuman, Demet Cansaran
dc.contributor.authorIDhttp://orcid.org/0000-0001-5662-2333tr_TR
dc.contributor.departmentBiyoteknoloji Enstitüsütr_TR
dc.contributor.otherYangın, Sevcan
dc.contributor.otherTanman, Ümmügülsüm
dc.date.accessioned2020-05-06T10:54:58Z
dc.date.available2020-05-06T10:54:58Z
dc.date.issued2019
dc.description.abstractIn order to find an effective solution to the treatment of cancer disease, many international collaborative researches have been carried out and many promising results have been obtained from these on going studies. An effective solution has not yet been found for cancer disease but studies on the development of new treatment methods and the findings of the research results continue to be published. In this context, in the studies focusing on the treatment of cancer, the findings obtained after the use of advanced technologies have been used in personalized medicine and clinical applications. Nowadays, next-generation sequencing technologies, which provide information on genomes with genome sequencing, are one of the most advanced technologies used in cancer research. Next-generation sequencing technology examines both genes and identifies some mutations. This technique enables the identification of unknown sequence variations in a short time and more easily, thus enabling clinicians to better understand the mechanisms of cancer. In this review, we aimed to provide information about the availability of next generation sequencing technology in pharmaceutical applications including areas such as tumor marker determination to pharmacogenomics, targeted therapy, precision medicine, vaccine treatment, biopharmaceutics, polypharmocology, toxgonostics and pharmacoepidemiology.tr_TR
dc.identifier.endpage486tr_TR
dc.identifier.issue4tr_TR
dc.identifier.startpage473tr_TR
dc.identifier.urihttps://doi.org/10.5505/TurkHijyen.2019.33576tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/71222
dc.identifier.volume76tr_TR
dc.language.isoentr_TR
dc.relation.isversionof10.5505/TurkHijyen.2019.33576tr_TR
dc.relation.journalTurk Hijyen ve Deneysel Biyoloji Dergisitr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectCancertr_TR
dc.subjectNext generation sequencingtr_TR
dc.subjectPharmaceutical applicationstr_TR
dc.titlePharmaceutical applications based on next generation sequencing technology in oncologic drug developmenttr_TR
dc.title.alternativeOnkolojik ilaç geliştirilmesinde yeni nesil dizileme teknolojisine dayali farmasötik uygulamalartr_TR
dc.typeArticletr_TR

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
CC_DD_Pharmaceutical applications based on next generation sequencing technology in oncologic drug development_.pdf
Size:
516.81 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.62 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Makale