Analysis of Bragg curve parameters and lateral straggle for proton and carbon beams

dc.contributor.authorEkinci, Fatih
dc.contributor.authorBostancı, Gazi Erkan
dc.contributor.authorDağlı, Özlem
dc.contributor.authorGüzel, Mehmet Serdar
dc.contributor.departmentBilgisayar Mühendisliğitr_TR
dc.contributor.facultyMühendislik Fakültesitr_TR
dc.date.accessioned2021-12-01T12:27:14Z
dc.date.available2021-12-01T12:27:14Z
dc.date.issued2021-07-01
dc.description.abstractHeavy ions have varying effects on the target. The most important factor in comparing this effect is Linear Energy Transfer (LET). Protons and carbons are heavy ions with high LET. Since these ions lose energy through collisions as they move through the tissue, their range is not long. This loss of energy increases along the way, and the maximum energy loss is reached at the end of the range. This whole process is represented by the Bragg curve. The input dose of the Bragg curve, full width at half maximum (FWHM) value, Bragg peak amplitude and position, and Penumbra thickness are important factors in determining which particle is advantageous in tumor treatment. While heavy ions move through the tissue, small deviations occur in their direction of travel due to Coulomb collisions. These small deviations cause lateral straggle in the dose profile. Lateral straggle is important in determining the type and energy of the particle used in tumor treatments close to critical organs. In our study, when the water phantom of protons and carbon beams with different energies is taken into consideration, the input dose, FWHM value, peak amplitude and position, penumbra thickness and lateral straggle are calculated using the TRIM code and the results are compared with Monte Carlo (MC) simulation. It was found that the proton has an average of 63% more FWHM and 53% more Penumbra than the carbon ion. The carbon ion has an average of 28-45 times greater Bragg peak amplitude at the same Bragg peak location than the proton. It was observed that the proton scattered approximately 70% more in lateral straggle. The difference was found to be around 1.32 mm. In line with all these results, the most commonly used proton and carbon heavy ions in hadron therapy applications were compared.tr_TR
dc.description.indexTrdizintr_TR
dc.identifier.endpage41tr_TR
dc.identifier.issn/e-issn2618-6462
dc.identifier.issue1tr_TR
dc.identifier.startpage32tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/76573
dc.identifier.volume63tr_TR
dc.language.isoentr_TR
dc.publisherAnkara Üniversitesi Fen Fakültesitr_TR
dc.relation.journalCommunications Faculty of Sciences University of Ankara Series A2-A3 Physical Sciences and Engineeringtr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectCarbon and proton ion radiotherapytr_TR
dc.subjectBragg curvetr_TR
dc.subjectTRIM Monte Carlotr_TR
dc.titleAnalysis of Bragg curve parameters and lateral straggle for proton and carbon beamstr_TR
dc.typeArticletr_TR

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