Progressive respiratory distress caused by a laryngeal histiocytic sarcoma in a European rabbit (Oryctolagus cuniculus)

Simple item page
dc.contributor.authorTAULESCU, Marian
dc.contributor.authorSOARE, Teodoru
dc.contributor.authorTOMA, Corina
dc.contributor.authorNEGOESCU, Andrada
dc.contributor.authorMURESAN, Cosmin
dc.contributor.authorLELESCU, Cristina
dc.contributor.departmentVeteriner Fakültesitr_TR
dc.date.accessioned2021-10-12T08:24:14Z
dc.date.available2021-10-12T08:24:14Z
dc.date.issued2021-09-27
dc.description.abstractHistiocytic sarcoma (HS) represents a rare type of malignant disease, characterized by neoplastic proliferation of interstitial dendritic cells (iDCs). In rabbits, there are only two previous reports of HS with pulmonary and cutaneous primary localizations. A 2-year-old, male, European rabbit (Oryctolagus cuniculus) with a clinical history of chronic respiratory distress and progressive weight loss was necropsied. Postmortem examination revealed a gray-white, well-demarcated ovoid mass that deformed the ventral region of the larynx. Similar nodules were identified in both lungs. Histologically, the laryngeal mass and pulmonary nodules were composed of dense sheets of neoplastic histiocytes with marked atypia and multinucleated neoplastic cells. Immunohistochemically, the neoplastic cells were intensely positive for Iba1, CD1a, and vimentin, occasionally for E-cadherin, and negative for multi-cytokeratin. A diagnosis of laryngeal HS with multiple pulmonary metastases was made. To the authors' knowledge, laryngeal histiocytic tumor has not been previously reported in rabbits.tr_TR
dc.identifier.endpage415tr_TR
dc.identifier.issn/e-issn1308-2817
dc.identifier.issue4tr_TR
dc.identifier.startpage411tr_TR
dc.identifier.urihttps://doi.org/10.33988/auvfd.777459tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/75421
dc.identifier.volume68tr_TR
dc.language.isoentr_TR
dc.publisherAnkara Üniversitesitr_TR
dc.relation.isversionof10.33988/auvfd.777459tr_TR
dc.relation.journalAnkara Üniversitesi Veteriner Fakültesi Dergisitr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectHystiocytic sarcomatr_TR
dc.subjectLarynxtr_TR
dc.subjectPulmonary metastasestr_TR
dc.titleProgressive respiratory distress caused by a laryngeal histiocytic sarcoma in a European rabbit (Oryctolagus cuniculus)tr_TR
dc.typeArticletr_TR

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
28.pdf
Size:
333.71 KB
Format:
Adobe Portable Document Format
Description:
Dergi
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.62 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Cilt:68 Sayı:04 (2021)