Investigation of Genotoxic, Antimicrobial and Antioxidant Activities of Leaf and Flower Extracts of Cynara syriaca Boiss

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dc.contributor.authorKaraşin, Nurhüda
dc.contributor.authorTolan, Veysel
dc.contributor.authorHaşimi, Nesrin
dc.contributor.authorDemirci, Özlem
dc.contributor.departmentZiraat Fakültesitr_TR
dc.date.accessioned2021-09-28T12:59:15Z
dc.date.available2021-09-28T12:59:15Z
dc.date.issued2019-09-05
dc.description.abstractThe mutagenicity and antimutagenicity of leaves and flower extract of Cynara syriaca Boiss were studied with Ames assay in Salmonella typhimurium TA98 and TA100 strains. While leaves extract did not show any mutagenic effects against all the tester strains with or without metabolic activation, the flower extract showed mutagenic effect against TA98 strain without metabolic activation. On the other hand, it has been observed that the extracts have antimutagenic activity against mutations induced by sodium azide and daunomycin. The antimicrobial activity of extracts was determined by disc diffusion and MIC value. Both of the extracts possess weak antimicrobial activity. Cupric reducing antioxidant capacity (CUPRAC), DPPH free radical scavenging activity, and ABTS radical cation decolorization methods were carried out to determine the antioxidant activity. Among the tested antioxidant methods, the highest antioxidant capacity was determined in ABTS radical cation decolorization assay in which both of the extracts exhibited the best effect. Flower extract exhibited higher activity also in DPPH free radical scavenging.tr_TR
dc.identifier.endpage353tr_TR
dc.identifier.issn/e-issn2148-9297
dc.identifier.issue3tr_TR
dc.identifier.startpage346tr_TR
dc.identifier.urihttps://doi.org/10.15832/ankutbd.410863tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/75003
dc.identifier.volume25tr_TR
dc.language.isoentr_TR
dc.publisherAnkara Üniversitesitr_TR
dc.relation.isversionof10.15832/ankutbd.410863tr_TR
dc.relation.journalTarım Bilimleri Dergisitr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectMutagenicitytr_TR
dc.subjectAntimutagenicitytr_TR
dc.subjectAntioxidant activitytr_TR
dc.titleInvestigation of Genotoxic, Antimicrobial and Antioxidant Activities of Leaf and Flower Extracts of Cynara syriaca Boisstr_TR
dc.typeArticletr_TR

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Cilt:25 Sayı:03 (2019)