Independent predictors of survival in endometrium cancer: platelet-to-lymphocyte ratio and platelet/neutrophil/monocyte-to-lymphocyte ratio

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dc.contributor.authorKar, İrem
dc.contributor.departmentTıp Fakültesitr_TR
dc.date.accessioned2020-12-30T12:56:24Z
dc.date.available2020-12-30T12:56:24Z
dc.date.issued2018
dc.description.abstractObjective: To evaluate the association between ratios of inflammatory markers and survival in endometrium cancer (EC). Material and methods: Four hundred ninety-seven patients with epithelial EC were included. The evaluated ratios were neutrophil (N)/lymphocyte (L), neutrophil count divided by the lymphocyte count; platelet (P)/lymphocyte, platelets divided by the lymphocyte count; lymphocyte/monocyte (M), lymphocytes divided by the monocyte count; NM/L, neutrophil plus monocyte divided by the lymphocyte count; PNM/L, the sum total counts of platelets, neutrophils and monocytes divided by the lymphocyte count. Results: The median follow-up time was 24 months (1-129). Recurrence and exitus occurred in 34 (7%) and 18 (3.7%) patients, respectively. Metastasis in pelvic or para-aortic lymph nodes were significantly related only with low L/M. None of the inflammatory ratios were associated with disease-free survival. In multi-variant analysis, only high P/L (>168) and high PNM/L (>171) were related with a statistically significant hazard ratio for death of 2.91 (p=0.024) and 2.93 (p=0.023), respectively. Conclusion: The P/L and PNM/L were in relation with worse overall survival and also independent prognostic factors for OS.tr_TR
dc.identifier.endpage86tr_TR
dc.identifier.issue2tr_TR
dc.identifier.startpage78tr_TR
dc.identifier.urihttps://doi.org/10.4274/jtgga.2017.0112tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/72611
dc.identifier.volume19tr_TR
dc.language.isoentr_TR
dc.relation.isversionof10.4274/jtgga.2017.0112tr_TR
dc.relation.journalJ Turk Ger Gynecol Assoc .tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectEndometrium cancertr_TR
dc.subjectplatelettr_TR
dc.subjectmonocytetr_TR
dc.titleIndependent predictors of survival in endometrium cancer: platelet-to-lymphocyte ratio and platelet/neutrophil/monocyte-to-lymphocyte ratiotr_TR
dc.typeArticletr_TR

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