General overvıew of the studıes wıth maldı-tof

dc.contributor.authorKocaman, Evrim
dc.contributor.departmentBiyoteknolojitr_TR
dc.contributor.facultyBiyoteknoloji Enstitüsütr_TR
dc.date.accessioned2021-11-30T07:17:51Z
dc.date.available2021-11-30T07:17:51Z
dc.date.issued2019
dc.description.abstractIn the 1980s, the discovery of a variety of soft ionization techniques provided the technical basis for the first time mass spectrometric detection and analysis of free, chemically polar, variable biopolymers and their degradation products. In recent years, Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has become a well-liked and multifaceted method to perform analyses of macromolecules which is the biological origin. This review provides a general overview of the areas of use of MALDI-TOF MS for biotechnological researches. MALDI-TOF MS is a way that supplies well-directed, affordable, and speedy identification of fungi, viruses, bacteria in clinical microbiological laboratories. Newly, this method has been successfully applied to DNA sequencing (genotyping) as well as mutation screening. Also, this way has the potential to become a conventional method for high throughput genotyping of single nucleotide polymorphisms (SNPs), both for biotechnology laboratories and for clinical applications. When it is compared with conventional and molecular identification methods, it makes a major contribution to minimizing the mortality rate and hospitalization period of the patients. It is more effective on per sample costs and elapsed time on working.tr_TR
dc.description.indexYoktr_TR
dc.identifier.issue1tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/76470
dc.identifier.volume28tr_TR
dc.language.isoentr_TR
dc.publisherAnkara Üniversitesi Fen Fakültesitr_TR
dc.relation.journalCommunications, Series C: Biologytr_TR
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectMALDI-TOFtr_TR
dc.subjectproteintr_TR
dc.subjectmicrobiologytr_TR
dc.titleGeneral overvıew of the studıes wıth maldı-toftr_TR
dc.typeArticletr_TR

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