Browsing by Author "Kibar, Murat"

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    Effects of medetomidine/ketamine and xylazine/ketamine anesthesia and their reversal by atipamezole on ocular parameters and monitored anesthesia care in cats
    (Ankara Üniversitesi Veteriner Fakültesi, 2022) Kibar, Murat; Other; Other
    The aim of this study was to investigate the impact of the general anesthetic drug ketamine and premedication agents medetomidine and xylazine, and their reversal by atipamezole, on monitored anesthesia care values and ocular parameters such as intraocular pressure, horizontal pupillar diameter, and Schirmer tear test in cats. A randomized, single-blinded study was conducted. Twenty intact female cats (weiging between 2.2 and 3.6 kg, and 0.5 to 5.5 years of age) referred for ovariohysterectomy (OHE) procedure by the owners at regular intervals over 4 months were included in the study. The cats were randomly divided into two groups containing 10 animals in each group. The cats were premedicated with medetomidine 80 µg/kg intramuscular in group 1 while the cats in the 2nd group were premedicated with xylazine hydrochloride 2 mg/kg intramuscular. After the OHE procedure was ended, anesthesia regimes were reversed by using atipamezole 200 µg/kg intramuscularly. Monitoring of respiration rate, heart rate, mean arterial pressure, peripheral arterial oxygen saturation, and body temperature were conducted using a patient monitor at T0, T1, T2, T3, and T4 time points. Both groups showed declines in intraocular pressure and increases in horizontal pupil diameter after anesthesia induction (T0 vs. T1, all, P<0.05); however, the chancing and recovery pattern of intraocular pressure and horizontal pupil diameter showed intergroup difference. In conclusion, xylazine/ketamine is more effective than medetomidine/ketamine in attenuating the intraocular pressure, increasing the horizontal pupil diameter, and alteration the monitored anesthesia care response in the general anesthesia.
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    Köpeklerde Escherichia coli ve Proteus mirabilis ile oluşturulan aşağı üriner sistem enfeksiyonu ve vezikoüreteral refluksla ilişkisi
    (2005) Özkanlar, Yunusemre; Şahal, Mehmet; Kibar, Murat; Sibel, Özkök
    : Bu çalışmada 14 köpek kullanıldı. Köpekler iki gruba ayrıldı. Salisilik asit’in etil alkoldeki % 0.1’lik solüsyonu ile idrar keseleri irrite edildikten sonra, I. grup Escherichia coli, II. grup Proteus mirabilis ile mililitrede 108 mikroorganizma bulunan solüsyon kullanılarak idrar keseleri enfekte edildi. Her iki gruptaki köpeklerde üriner sistem enfeksiyonu oluşturulmadan önce, enfeksiyon oluşturulduktan sonra 7. gün ve sağaltım tamamlandıktan sonra meydana gelen klinik, laboratuar, hematolojik, biyokimyasal, radyolojik, ultrasonografik, mikrobiyolojik, patolojik bulgular incelendi. Vezikoüreteral refluks (VUR) oluşan birer erkek köpek sağaltılmayarak araştırmanın 14. günü ötenazi edilip nekropsileri yapıldı. Retrograd üretrasistografi sonuçlarına göre, Escherichia coli ile enfekte edilen 7 köpekten 3’ünde (% 42.9), Proteus mirabilis ile enfekte edilen 7 köpekten 4’ünde (% 57.1) VUR oluştu. VUR oluşan köpeklerde yukarı üriner sistem enfeksiyonuna ait bulguların varlığı tespit edildi. Sağaltımdan sonra, bir köpek hariç diğerlerinde VUR’un ortadan kalktığı belirlendi. Sonuç olarak, köpeklerde aşağı üriner sistem enfeksiyonunda mikroorganizmanın türü, enfeksiyonun süresi ve şiddetine bağlı olarak 2. derece sekonder VUR gelişebileceği, radyografik yöntemle VUR’un tanısının konulabileceği ve etkin medikal sağaltımla hastalığın büyük oranda düzeltilebileceği (% 80) tespit edildi. Fourteen dogs were used in this study. The dogs were divided into two groups. Urinary bladders were infected by an inoculum in concentration of 108 colony-forming units (cfu) contained Proteus mirabilis for group I and Escherichia coli for group II, after irritating all bladders by 0.1 % salicylic acid in ethanol. Clinical, laboratory, hematological, biochemical, radiological, ultrasonographical, microbiological and pathological findings were obtained in both groups before the urinary tract infection, on 7th day of the urinary tract infection and after the treatment. The two male dogs with vesicoureteral reflux were euthanized on 14th day of the investigation and necropsies were performed. According to the findings of retrograde uretrocystography, vesicoureteral reflux detected in three out of seven dogs (42.9 %) on the Escherichia coli group and four out of seven dogs (57.1 %) on the Proteus mirabilis group. The findings of upper urinary tract infection were detected in the dogs with VUR. After the treatment, VUR was cured in all of the dogs except for one dog. Finally, second degree secondary VUR was induced according to microorganism, time and severity of the infection in the dogs with lower urinary tract infection. VUR may be diagnosed by radiography and cured (80 %) with the effective medical treatment.
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    Microtia and anotia in a dog
    Kibar, Murat
    Trdizin