Synthesis and structure of 2-[(5,6,7,8-tetrahydro-5,5,8,8tetramethyl-2-naphthalene)]-5-benzimidazole ethylcarboxylate monohydrat
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Date
2000
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Abstract
Aspartofaprograminvestigatingtheconformationsofpotentialanticarcinogensandantioxidants, the structure of the title compound C24H28N2O2 H2O is reported. The monohydrate crystallizes in the monoclinic space group P2/c with unit cell parameters a 16.184(1), b 7.937(1), c 16.968(1), 92.788(7) , and Z 4. The benzimidazole and tetrahydrotetramethylnaphthalene ring systems are inclined to one another by approximately 26 . The water molecule plays an important role in the crystal structure by hydrogen bonding to different functional groups of three organic moieties. Additional crystal stabilization is due to – stacking of benzimidazole rings.
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Keywords
Anticarcinogenic/antioxidant, Benzimidazole, Retinoic acid analog