A retrospective comparative study of prednisolone use in antagonist co-treated assisted reproductive technology cycles for patients with good prognosis
| dc.contributor.author | Özmen, Batuhan | |
| dc.contributor.department | Tıp Fakültesi | tr_TR |
| dc.date.accessioned | 2020-12-04T09:02:56Z | |
| dc.date.available | 2020-12-04T09:02:56Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | Objective: To investigate the impact of peri-implantation prednisolone use and its duration in antagonist co-treated assisted reproductive technology (ART) cycles of patients with good prognosis. Materials and methods: Infertile patients treated with gonadotropin-releasing hormone antagonist protocol between January 2010 and June 2013 were included. The patients in group A (n=196) received no prednisolone. The patients in groups B (n=397) and C (n=371) received 5 mg oral prednisolone daily, for 4 and 12 days following embryo transfer, respectively. The main outcome parameter was live birth rate. Results: The ages of the groups were 30.1±4.6, 31.5±4.5, and 30.9±4.7 years, respectively (p=0.163). There was no statistically significant difference between the groups regarding cycle characteristics. Implantation rates were 20.7%, 24.6%, and 23.8%, respectively (p=0.163). Miscarriage rates were 1.5%, 3.5%, and 3.2%, respectively (p=0.859). Live birth rates were 28.7%, 29.3%, and 32.8%, respectively (p=0.482). Conclusion: Empiric prednisolone administration during the peri-implantation period does not seem to have beneficial effects in ART cycles of patients with good prognosis. | tr_TR |
| dc.description.index | Pubmed | |
| dc.identifier.endpage | 151 | tr_TR |
| dc.identifier.issue | 3 | tr_TR |
| dc.identifier.startpage | 147 | tr_TR |
| dc.identifier.uri | https://doi.org/10.4274/tjod.12244 | tr_TR |
| dc.identifier.uri | http://hdl.handle.net/20.500.12575/72532 | |
| dc.identifier.volume | 15 | tr_TR |
| dc.language.iso | en | tr_TR |
| dc.relation.isversionof | 10.4274/tjod.12244 | tr_TR |
| dc.relation.journal | Turk J Obstet Gynecol . | tr_TR |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | tr_TR |
| dc.subject | Assisted reproductive technology | tr_TR |
| dc.subject | glucocorticoid | tr_TR |
| dc.subject | gonadotropin-releasing hormone antagonist | tr_TR |
| dc.title | A retrospective comparative study of prednisolone use in antagonist co-treated assisted reproductive technology cycles for patients with good prognosis | tr_TR |
| dc.type | Article | tr_TR |