Diyarbakır bölgesinde yapılan otopsilerde alınan karaciğer ve böbrek örneklerinde kurşun düzeylerinin tespiti
The aim of this study was to determine of the level of most abundant heavy metal like lead which is explosured by many different factors, from human liver, kidney cortex and kidney medulla tissues of the autopsy cases and to search the correlation of the lead levels between tissues. Autopsy tissues of individuals who were 77 males, 23 females totaly 100 between 18 to 90 years old collected in Council of Forensic Medicine, Diyarbakir Group Chairmanship, Diyarbakir. Liver and kidney tissue samples were ignited in microwave oven with nitric acid before the analysis. Lead were analyzed by Inductively coupled plasma mass spectrometry (ICP-MS). Average value of lead level in liver, kidney cortex and kidney medulla tissues was found respectively as 375,24±325,46 (106,83-1932,08) ppb, 304,65±265,86 (61,68-1771,94) ppb, 281,42±255,47 (52,57-1585,11) ppb. The correlation of the results with individual informations was assessed by SPSS 15.0 statistical programme. Lead levels in liver tissues were found greater than in kidney tissues and significant positive correlation was found between liver-cortex (r= 0,913; p< 0,001) and liver-medulla (r=0,896; p< 0,001). Also lead levels in kidney-cortex tissues were found greater than in kidney medulla tissues and significant positive correlation was found between the kidney fragments (r= 0,949; p< 0,001). Significant positive correlation was shown in between age and lead levels just in liver tissues (r= 0,204; p< 0,05). It is also found that smoking habit is one of the most effective parameter for lead accumulation in all tissues (medulla p< 0,01; cortex p< 0,05; liver p<0,01). There was significant increase in lead levels in city residents than in rural areas (p< 0,05). There was significant relation found between lead levels in all tissues and occupations of the individuals (kidney fragments p<0,01 and liver p<0,001).