Tüm vücut ışınlamalarında 6 MV ve 18 MV foton enerjilerinde doz dağılımlarının tedavi planlama sistemi ve in-vivo dozimetri ile karşılaştırılması
Özet
Total Body Irradiation (TBI) is a special method of radiotherapy with a high skin source distance (SSD). TBI has an important role in bone marrow transplantation. Purpose of the TBI treatment is destroying the patient's bone marrow elements and create the appropriate environment to settle for given that the bone marrow cells. In the ideal TBI treatment, dose distribution must be homogeneous. But dose uniformity fails because of the variable of the body's anatomy and differences in density of tissue (muscle, bone, air). Lateral TBI treatment plan was done on Eclipse Treatment Planning System (TPS) by using Varian Clinac DHX Linear Accelerator for Alderson rando phantom. 6 MV and 18 MV photon energies are used in these plans. Skin doses were detected by Thermoluminescent Dosimetry (TLD) and TPS. And midline doses were detected by TLD, Metal-Oxide Semiconductor Field Effect Transistor (MOSFET) and TPS. Measurement results of TPS and in-vivo dosimetry were compared. Thus, the harmony between TPS and in-vivo dosimetry was tested. When measurement datas were analyzed, the dose distribution in 18 MV more uniform than the dose distribution in 6 MV. Also missing of mediastinal dose completed with 18 MV photon energy. Values of the doses were compared between using MOSFET and TLD dosimeters. In measuring the integral dose with TLD-100 dosimeters were compared MOSFET dosimeter system to be more accurate and meaningful results by the system. The results obtained were found consistent with the literature.