Kronik maksiller sinüs açıklığı olan hastalarda immunohistokimyasal bir araştırma
Chronic maxillary sinus openings (CMSO) or oroantral fistulaes are usually larger than acute maxillary sinus communications and occur if the sinus perforation could not noticed or treated unsuccesfully.In this study, 18 male, 2 female totally 20 patients who diagnosed as chronic maxillary sinus perforation, have been treated surgically following the clinical and radiological examination.Pathological tissues from maxillary sinus and fistulaes, changes in the composition of glicoconjugates which takes place in the structure of mucus, barrier of mucous membrane, have been where evaluated immunohistochemically by using lectins.Five lectins; four of them marked by biotin, one did not, were used. Lectins marked by biotin are, Concanavaline A (Con A), Dolchos biphlorous (DBA), Ulex europaes agglutinin (UEA-1), Lens culinaris agglutinin (LcH). A lectin that did not marked is Phaseolus vulgaris agglutinin (PHA-P).Changes in the composition of glicoconjugates which occur in the epithelium of mucous membrane presented immunohistochemically by using five lectins four of them marked by biotin (Con A, DBA, UEA-1, LcH), one did not (PHA-P).Radiologic evaluations were performed to detect whether septum deviation or concha hypertrophy or both were present in CMSO patients. Presence of deviated septum or hypertophic concha or both may be the reason of chronic maxillary diseases. All patients were evaluated in order to find out chronic sinusitis history. It is concluded that chronic maxillary sinus diseases are accompanying factors in CMSO formings related to dental extractions.