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dc.contributor.authorAkçelik, Nefise
dc.contributor.otherKaraca, Başar
dc.contributor.otherAkçelik, Mustafa
dc.date.accessioned2020-05-27T12:36:46Z
dc.date.available2020-05-27T12:36:46Z
dc.date.issued2015
dc.identifier.urihttps://doi.org/10.2298/ABS141120114Ktr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/71246
dc.description.abstractOver the last decades, several antimicrobial agents have been made available. Due to increasing antimicrobial resistance, bacteriophages were rediscovered for their potential applications against bacterial infections. In the present study, biofilm inhibition and eradication of Salmonella enterica subsp. enterica serovar Typhimurium DMC4 strain (S. Typhimurium) was evaluated with respect to different incubation periods at different P22 phage titrations. The efficacy of P22 phage on biofilm formation and eradication of S. Typhimurium DMC4 strain was screened in vitro on polystyrene and stainless steel surfaces. The biofilm forming capacity of S. Typhimurium was significantly reduced at higher phage titrations (106 pfu/mL≤). All phage titers (104-108 pfu/mL) were found to be effective at the end of the 24 h-incubation period whereas higher phage titrations were found to be effective at the end of the 48 h and 72 h of incubation. P22 phage has less efficacy on already formed, especially mature biofilms (72 h-old biofilm). Notable results of P22 phage treatmenton S. Typhimurium biofilm suggest that P22 phage has potential uses in food systems.tr_TR
dc.language.isoentr_TR
dc.relation.isversionof10.2298/ABS141120114Ktr_TR
dc.subjectBacterial adhesiontr_TR
dc.subjectBacteriophagetr_TR
dc.subjectBiofilmtr_TR
dc.subjectEradicationtr_TR
dc.subjectSalmonellatr_TR
dc.titleEffects of P22 bacteriophage on Salmonella enterica subsp. enyerica serovar Typhimurium DMC4 strain biofilm formation and eradicationtr_TR
dc.typeArticletr_TR
dc.relation.journalArchives of Biological Sciencestr_TR
dc.contributor.departmentBiyoteknoloji Enstitüsütr_TR
dc.identifier.volume67tr_TR
dc.identifier.issue4tr_TR
dc.identifier.startpage1361tr_TR
dc.identifier.endpage1367tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR


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