Scopus İndeksli Yayınlar
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Diverse Responses of Neurons and Monocytes to Titanium Dioxide Nanoparticle Exposure
(2019)Introduction: The toxicity of titanium dioxide nanoparticles (TiO2NPs) in neurons occurs by glutamate signaling via N-methyl-d-aspartate (NMDA) receptors. Although cellular uptake of TiO2NPs may lead to oxidative stress ... -
Optimization of gene expression microarray protocol for formalin-fixed paraffin-embedded tissues
(2016)Formalin-fixed paraffin-embedded (FFPE) tissue is a widely available clinical specimen for retrospective studies. The possibility of long-term clinical follow-up of FFPE samples makes them a valuable source to evaluate ... -
Hemoglobin alpha 2 gene +861 G>A polymorphism in Turkish population
(2011)Thalassemia is an inherited blood disorder which is divided into two groups: alpha and beta. HBA1 and HBA2 are the two genes associated with alpha thalassemia. The aim of this study is to investigate abnormal hemoglobin ... -
Genome-Wide Transcriptional Reorganization Associated with Senescence-to-Immortality Switch during Human Hepatocellular Carcinogenesis
(2013)Senescence is a permanent proliferation arrest in response to cell stress such as DNA damage. It contributes strongly to tissue aging and serves as a major barrier against tumor development. Most tumor cells are believed ... -
Differential expression of selected histone modifier genes in human solid cancers
(2006)Background: Post-translational modification of histones resulting in chromatin remodelling plays a key role in the regulation of gene expression. Here we report characteristic patterns of expression of 12 members of 3 ... -
Genome projects 5W1H: What, where, when, why, how and in which population?
(2014)Genome projects aim to decode an organism's complete set of deoxyribonucleic acid (DNA), which can be described as the living code of organism. The idea of the Human Genome Project (HGP) was conceived in the early 1980s. ... -
Comparison of high-resolution melting analysis to denaturing high performance liquid chromatography in the detection of point mutations in MEFV, F5, and F2 genes
(2014)Background/aim: Sensitive and cost-effective detection of point mutations is important in genetics research. Denaturing highperformance liquid chromatography (DHPLC) is known to be one of the most sensitive techniques for ... -
Protocol for qRT-PCR analysis from formalin fixed paraffin embedded tissue sections from diffuse large b-cell lymphoma: Validation of the six-gene predictor score
(2016)As a part of an international study on the molecular analysis of Diffuse Large B-cell Lymphoma (DLBCL), a robust protocol for gene expression analysis from RNA extraction to qRT-PCR using Formalin Fixed Paraffin Embedded ... -
Prospective international cohort study demonstrates inability of interim PET to predict treatment failure in diffuse large B-cell lymphoma
(2014)The International Atomic Energy Agency sponsored a large, multinational, prospective study to further define PET for risk stratification of diffuse large B-cell lymphoma and to test the hypothesis that international ... -
Measurements of inclusive and differential fiducial cross-sectionsoft ̄tγproduction in leptonic final states at√s=13 TeV in ATLAS
(2019)Inclusive and differential cross-sections for the production of a top-quark pair in association with a photon are measured with proton-proton collision data corresponding to an integrated luminosity of 36.1 fb-1, collected ... -
Performance of top-quark andW-boson tagging with ATLAS inRun 2 of the LHC
(2019)The performance of identification algorithms (“taggers”) for hadronically decaying top quarks and W bosons in pp collisions at s = 13 TeV recorded by the ATLAS experiment at the Large Hadron Collider is presented. A set ... -
Searches for third-generation scalar leptoquarks inps= 13TeVppcollisions with the ATLAS detector
(2019)Limits are set on the pair production of scalar leptoquarks, where all possible decays of the leptoquark into a quark (t, b) and a lepton (τ, ν) of the third generation are considered. The limits are presented as a function ... -
Measurement ofW±Zproduction cross sections and gauge bosonpolarisation inppcollisions at√s=13 TeV with the ATLASdetector
(2019)This paper presents measurements of W±Z production cross sections in pp collisions at a centre-of-mass energy of 13 TeV. The data were collected in 2015 and 2016 by the ATLAS experiment at the Large Hadron Collider, and ... -
Observation of electroweak W±Zboson pair production in association with two jets in ppcollisions at √s=13 TeV with the ATLAS detector
(2019)An observation of electroweak W±Z production in association with two jets in proton–proton collisions is presented. The data collected by the ATLAS detector at the Large Hadron Collider in 2015 and 2016 at a centre-of-mass ... -
Investigation of the synthesis of some dehydroalanine derivatives
(2000)Dehydroamino acids represent an important class of compound as they are key intermediates in unusual amino acid and in the design of peptides and are constituents of a variety of naturally occurring antibiotic and phytotoxic ... -
Rat lung aldose reductase inhibition capacity of substituted indole hydrazide/hydrazone derivatives
(2012)Diabetes Mellitus is one of the most serious health problem facing both developed and developing countries. Long term complications lead to morbidity and mortality in patients with diabetes. Increased polyol pathway has ... -
Synthesis and antioxidant activity evaluations of melatonin-based analogue indole-hydrazide/hydrazone derivatives
(2012)Melatonin (MLT) is a hormone synthesized from the pineal gland. It is a direct scavenger of free radicals, which is related to its capability to defend cells from oxidative stress. Recently MLT-related compounds are under ... -
Antimicrobial evaluation of indole-containing hydrazone derivatives
(2011)There has been an increasing importance of drug-resistant pathogens in clinical microbiological and antibacterial research. Indoles and hydrazone-type compounds constitute important classes of compounds in the search for ... -
Evaluation of rat kidney aldose reductase inhibitory activity of some N-acetyl dehydroalanine derivatives
(2011)Aldose reductase (AR) is an enzyme that catalyzes the conversion of glucose to sorbitol, which is in turn converted to fructose by sorbitol dehydrogenase. Increased AR activity has been implicated in the pathogenesis of ... -
Melatonin analogue new indole hydrazide/hydrazone derivatives with antioxidant behavior: Synthesis and structureactivity relationships
(2009)Melatonin (MLT) is a hormone produced in the brain by the pineal gland, from the amino acid tryptophan. It is also an antioxidant hormone with a particular role in the protection of nuclear and mitochondrial DNA. In recent ...