| dc.contributor.author | Süzen, Sibel | |
| dc.contributor.author | Seçkin, Özden | |
| dc.contributor.author | Shirinzadeh, Hanif | |
| dc.date.accessioned | 2019-06-27T13:32:00Z | |
| dc.date.available | 2019-06-27T13:32:00Z | |
| dc.date.issued | 2010 | |
| dc.identifier.other | 10.3390/molecules15042187 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12575/66846 | |
| dc.identifier.uri | https://doi.org/10.3390/molecules15042187 | |
| dc.description.abstract | The aim of this study was to synthesize and examine possible in vitro antioxidant effects of indole-based melatonin analogue compounds. As a part of our ongoing study nineteen indole hydrazide/hydrazone derivatives were synthesized, characterized and their in vitro antioxidant activity was investigated by three different assays: by evaluating their reducing effect against oxidation of a redox sensitive fluorescent probe, by examining their protective effect against H(2)O(2)-induced membrane lipid peroxidation and by determining their inhibitory effect on AAPH-induced hemolysis of human erythrocytes. The results indicated significant strong antioxidant activity for most of the compounds, when compared to melatonin. | tr_TR |
| dc.description.abstract | Scopus | |
| dc.language.iso | en | tr_TR |
| dc.relation.isversionof | 10.3390/molecules15042187 | |
| dc.subject | Indole | tr_TR |
| dc.subject | Hydrazone | tr_TR |
| dc.subject | Hydrazide | tr_TR |
| dc.subject | Melatonin | tr_TR |
| dc.subject | Synthesis | tr_TR |
| dc.subject | Antioxidant activity | tr_TR |
| dc.title | Novel indole-based analogs of melatonin: synthesis and in vitro antioxidant activity studies | tr_TR |
| dc.type | Article | tr_TR |
| dc.relation.journal | Molecules | tr_TR |
| dc.contributor.department | Eczacılık Fakültesi | tr_TR |
| dc.identifier.volume | 15 | tr_TR |
| dc.identifier.issue | 04 | tr_TR |
| dc.identifier.startpage | 2187 | tr_TR |
| dc.identifier.endpage | 2202 | tr_TR |
| dc.description.index | Wos | |
