Search
Now showing items 41-45 of 45
Investigation of antimicrobial activities of indole-3-aldehyde hydrazide/hydrazone derivatives
(2008)
Background: Indoles and hydrazone-type compounds constitute an important class of compounds for new drug development in order to discover an effective compound against multi-drug-resistant microbial infections. Methods: A ...
Screening and evaluation of antioxidant activity of some pyridazine derivatives
(2008)
Antioxidants are compounds that can delay, inhibit, or prevent the oxidation of materials that can be oxidized by scavenging free radicals and help in diminishing oxidative stress. They belong to different chemical classes. ...
Anti-cancer activity studies of indolalthiohydantoin (PIT) on certain cancer cell lines
(2000)
5-(2-Phenyl-3′-indolal)-2-thiohydantoin (PIT) has been evaluated as an anti-cancer compound on several cancer lines organised in to subpanels representing leukemia, melanoma, and cancer of lung, colon, kidney, ovary, breast, ...
A comparative study: Evaluation of antioxidant activity of melatonin and some indole derivatives
(2005)
To understand antioxidant activity and the role played by melatonin, we have designed and tested several new compounds. We present the results in terms of structure-activity relationships, focusing on the lack of the methoxy ...
Pharmacological Applications of Nrf2 Inhibitors as Potential Antineoplastic Drugs
(2019)
Oxidative stress (OS) is associated with many diseases ranging from cancer to neurodegenerative disorders. Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) is one of the most effective cytoprotective controller against ...