Summary. The aldose reductase enzyme, involved in the sorbitol pathway which is an important mechanism in regulation of mammalian glucose metabolism, has been known to play a significant role in the initiation of diabetic ...

The anti-HIV activity of the previously synthesized S-( 2-phenyl-3’-indolal)-Zthiohydantoin I was evaluated. The compound, containing two structural moieties found in highly active anti-HIV agents, exhibited poor activity ...