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Blood group genotyping in multi-transfused patients
İnce, Elif (2013-02-25)Background: In chronically transfused patients, the classical hemagglutinati on assays may be inaccurate in defining the RBC phenotypes of the patients due to previous transfusions. Design: DNA samples from 39 multi-transfused ... -
Hemoglobin alpha 2 gene +861 G>A polymorphism in Turkish population
Özdag, Hilal (2011)Thalassemia is an inherited blood disorder which is divided into two groups: alpha and beta. HBA1 and HBA2 are the two genes associated with alpha thalassemia. The aim of this study is to investigate abnormal hemoglobin ... -
Relation of Soluble Endothelial Protein C Receptor and Cytokines After Allogeneic Hematopoietic Stem Cell Transplantation
İnce, Elif (2009-08-18)Aim: The objective of this study was to elucidate the effects of tumor necrosis factor a (TNF-a), interleukin 1b (IL-1b), interleukin 2 (IL-2), interleukin 6 (IL-6), and interleukin 8 (IL-8) on the expression of soluble ... -
Relationship between functional promoter polymorphism in the XBP1 Gene (-116C/G) and obesity
Yılmaz, Erkan (2010)Endoplasmic reticulum stress is a central feature of obesity, insulin resistance, and type 2 diabetes. A polymorphism of the XBP1 gene (-116C/G), a transcription factor that modulates the endoplasmic reticulum stress ... -
Reversible protease-activated receptor 1 downregulation mediated by ankaferd blood stopper inducible with lipopolysaccharides inside the human umbilical vein endothelial cells
Yılmaz, Erkan (2011)Ankaferd Blood Stopper (ABS) is a novel topical hemostatic agent with pleiotropic actions indicated in clinical hemorrhages. Protease-activated receptor 1 (PAR-1) is located in the crossroads of hemostasis, inflammation, ... -
Role of ZIP14 (SLC39A14) gene histidine rich regions in neural tube defects
Yılmaz, Erkan (2011)Neural tube defects (NTDs) comprise a group of congenital malformations that includes spina bifida, anencephaly, meningomyelocele and encephalocele. Reports have implicated zinc deficiency as one of the causative factors ...