Show simple item record

dc.contributor.authorBURGAZ YILMAZ, Emine Vildan (Yazar)
dc.contributor.authorPEKEL, A. Tarık (Tez Danışmanı)
dc.date.accessioned2019-02-07T18:41:12Z
dc.date.available2006
dc.date.available2019-02-07T18:41:12Z
dc.identifier.urihttp://hdl.handle.net/20.500.12575/30568
dc.description.abstractBu tez, elektrokimyasal yöntemle sentezlenen mangan(III) asetat aracılığıyla 3oksopropannitrillerin α,β-doymamış amitlerle radikalik halkalaşma reaksiyonlarıtemeline dayanmaktadır. Bu reaksiyonlar sonucunda 4-siyano-2,3-dihidrofuran-3karboksiamitbileşiklerieldeedildi. Çalışmada 3-oksopropannitril olarak; 3-fenil-3-oksopropannitril (1a), 3-(4-metilfenil)3-oksopropannitril (1b), 3-(4-metoksifenil)-3-oksopropannitril (1c), 3-(4-klorfenil)-3oksopropannitril (1d), 3-(2-tiyenil)-oksopropannitril (1e), 3-(2-furil)-oksopropannitril(1f) ve 3-(2-benzofuroil)-3-oksopropannitril (1g) ve 4,4-dimetil-3-oksopentannitril (1h)ve α,β-doymamış amit olarak; (2E)-3-tiyen-2-il-akrilamit (2a), (2E)-3-(2-furil)akrilamit(2b), (2E)-3-(5-metil-2-furil)akrilamit (2c), (2E) ve (2Z)-3-fenilakrilamit (2d) ve (2E,4E)-5-fenilpenta-2,4-dienamit (2e) kullanıldı. 3-Oksopropannitrillerin 2a ve 2c alkenleri ile radikalik halkalaşma reaksiyonlarısonucunda 4-siyano-2,3-dihidrofuran-3-karboksiamit bileşikleri elde edildi. Fakat bu 3-oksopropannitrillerin 2b ve 2d ile reaksiyonlarında hiçbir ürün oluşmadı. Ayrıca, (2E,4E)-5-fenilpenta-2,4-dienamitin (2e) 1a-h ile reaksiyonlarında alkenil sübstitüe 4siyano-2,3-dihidrofuranbileşikleri elde edildi. Bu bileşiklerin yapıları; IR, 1H-NMR, 13C-NMR, LC-MS spektrumları ile aydınlatıldı.AbstarctThis study is based on the radical cyclization reactions of 3-oxopropanenitriles with α,βunsaturatedamides mediated manganese(III) acetate which is synthesized byelectrochemical method. By the end of these reactions 4-cyano-2,3-dihydrofuran-3carboxyamidecompoundswereformed. 3-phenyl-3-oxopropanenitrile (1a), 3-(4-metylphenyl)-3-oxopropanenitrile (1b), 3-(4metoxyphenyl)-3-oxopropanenitrile (1c), 3-(4-chlorophenyl)-3-oxopropanenitrile (1d),3-(2-tienyl)-oxopropanenitrile (1e), 3-(2-furyl)-oxopropanenitrile (1f) 3-(2benzofuroyl)-3-oxopropanenitrile (1g) and 4,4-dimetyl-3-oxopentanenitrile (1h)compounds were used as 3-oxopropanenitriles and (2E)-3-tien-2-yl-acrylamide (2a),(2E)-3-(2-furyl)acrylamide (2b), (2E)-3-(5-metyl-2-furyl)acrylamide (2c), (2E) and(2Z)-3-phenylacrylamide (2d) and (2E, 4E)-5-phenylpenta-2,4-dienamide (2e)compounds were used as α,β-unsaturated amides. 4-cyano-2,3-dihydrofuran-3-carboxyamide compounds were synthesized by the radical cyclization reactions with 3-oxopropanenitriles and 2a and 2c alkenes. However noproducts were observed with the reactions between 3-oxopropanenitriles and 2b and 2d.Also, alkenyl substituted 4-cyano-2,3-dihydrofuran compounds were formed with thereactions between (2E, 4E)-5-phenylpenta-2,4-dienamide (2e) and 1a-h. The structureof these compounds were identified with spectroscopic methods.
dc.language.isotrTR_tr
dc.publisherAnkara Üniversitesi Fen Bilimleri Enstitüsü Kimya Anabilim Dalı
dc.subjectBİLİM, Kimyatr
dc.title3-Oksopropannitrillerin mangan(III) asetat aracılığında α,ßdoymamış amitlerle radikalik halkalaşma reaksiyonları
dc.typeThesis


Files in this item

This item appears in the following Collection(s)

Show simple item record