Now showing items 1-10 of 22
İndol Türevi Yeni Bir Bileşik İle Sıçanlarda Radyasyon Nefropatisinin Engellenmesi
Bu çalışmada yeni sentezlenmiş bir indol türevi bileşiğin radyasyona sekonder gelişen nefropatiyi engelleyici etkisi olup olmadığı araştırıldı. Bu amaçla yirmi sekiz erkek Wistar sıçan dört gruba ayrıldı: Yalnız radyoterapi, ...
Synthesis and evaluation of in vitro antioxidant capacities of some benzimidazole derivatives
New, except 1d, melatonin analogue benzimidazole derivatives were synthesized and characterized in the present study. The potential role of melatonin as an antioxidant by scavenging and detoxifying ROS raised the possibility ...
Melatonin analogue new indole hydrazide/hydrazone derivatives with antioxidant behavior: Synthesis and structureactivity relationships
Melatonin (MLT) is a hormone produced in the brain by the pineal gland, from the amino acid tryptophan. It is also an antioxidant hormone with a particular role in the protection of nuclear and mitochondrial DNA. In recent ...
Determination and investigation of electrochemical behaviour of 2-phenylindole derivatives: discussion on possible mechanistic pathways
Some 2-phenyl indole (2PI) derivatives were investigated electroanalytically by voltammetric determination. The electrochemical behaviour of the 2PI derivatives were studied as a function of pH at a glassy carbon and hanging ...
In vivo metabolism of2-[1'-phenyl-3'-(3chlorophenyl)-2'-propenylyden]hydrazino-3-methyl4(3H)-quinazolinone in rats
The aim of this study was to investigate by HPLC the in vivo metabolism of 2-[1'-phenyl-3'-(3-chlorophenyl)-2'propenylyden]hydrazino-3-methyl-4(3H)-quinazolinone as a substrate, and as a model compound in rats. The substrate ...
Synthesis and structure of 2-[(5,6,7,8-tetrahydro-5,5,8,8tetramethyl-2-naphthalene)]-5-benzimidazole ethylcarboxylate monohydrat
Aspartofaprograminvestigatingtheconformationsofpotentialanticarcinogensandantioxidants, the structure of the title compound C24H28N2O2 H2O is reported. The monohydrate crystallizes in the monoclinic space group P2/c with ...