Now showing items 41-43 of 43
Anti-cancer activity studies of indolalthiohydantoin (PIT) on certain cancer cell lines
5-(2-Phenyl-3′-indolal)-2-thiohydantoin (PIT) has been evaluated as an anti-cancer compound on several cancer lines organised in to subpanels representing leukemia, melanoma, and cancer of lung, colon, kidney, ovary, breast, ...
A comparative study: Evaluation of antioxidant activity of melatonin and some indole derivatives
To understand antioxidant activity and the role played by melatonin, we have designed and tested several new compounds. We present the results in terms of structure-activity relationships, focusing on the lack of the methoxy ...
Pharmacological Applications of Nrf2 Inhibitors as Potential Antineoplastic Drugs
Oxidative stress (OS) is associated with many diseases ranging from cancer to neurodegenerative disorders. Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) is one of the most eﬀective cytoprotective controller against ...