5-(2-Phenyl-3′-indolal)-2-thiohydantoin (PIT) has been evaluated as an anti-cancer compound on several cancer lines organised in to subpanels representing leukemia, melanoma, and cancer of lung, colon, kidney, ovary, breast, ...

To understand antioxidant activity and the role played by melatonin, we have designed and tested several new compounds. We present the results in terms of structure-activity relationships, focusing on the lack of the methoxy ...

Oxidative stress (OS) is associated with many diseases ranging from cancer to neurodegenerative disorders. Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) is one of the most effective cytoprotective controller against ...