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Now showing items 21-30 of 5533
Design, synthesis, antimicrobial and antifungal activities of new 1,2,4-triazole derivatives containing 1h-tetrazole moiety
(Ankara Üniversitesi, 2020)
Objective: Antimicrobials and antifungals are the most acquired drugs in the world. Today, it becomes
necessary to create new drugs with antimicrobial and antifungal effect. The purpose of our research is the
synthesis ...
Medicinal plants traditionally used to treat skin diseases in Turkey – eczema, psoriasis, vitiligo
(Ankara Üniversitesi, 2020)
Objective: Different types of skin diseases negatively affect the lives of many people, both physically and
mentally. Here, we aimed to document medicinal plants used as traditional folk medicine for the treatment of
eczema, ...
Chemical characterization of the fatty acid compositions and antimicrobial activity of sumac (rhus coriaria l.) fruits, growing naturally in Turkey and sold in herbalist markets
(Ankara Üniversitesi, 2020)
Objective: The aim of this study was to compare the fatty acid components and antimicrobial properties of
R. coriaria L. samples which were sold as powder and grains that show natural distribution in Tunceli and
Siirt.
Material ...
Formulation and detailed characterization of voriconazole loaded in situ gels for ocular application
(Ankara Üniversitesi, 2020)
Objective: This study was aimed to prepare, characterize and evaluate in situ gel formulation for a
sustained ocular delivery of voriconazole.
Material and Method: In situ gels were prepared with three different hydrophilic ...
Synthesis and antiradical activity of alkyl derivatives of 5-(5-methyl-1h-pyrazol-3-yl)-4-phenyl-4h1,2,4-triazole-3-thiol
(Ankara Üniversitesi, 2020)
Objective: The aim of the work was to develop effective methods for the synthesis of biologically active
heterocyclic systems containing 1,2,4-triazole and pyrazole.
Material and Method: Chemical structures of synthesized ...
Pharmacophore modeling studies on known mmp-9 enzyme inhibitors to identify the important common features
(Ankara Üniversitesi, 2020)
Objective: In this study, pharmacophore models were generated to explain the structure–activity relationships
by using the known MMP-9 inhibitors.
Material and Method: Pharmacophore models were generated to explain the ...
Microwave synthesis of new 3-(alkylthio)-5-(thiophen2-ylmethyl)-1,2,4-triazol-4-amines
(Ankara Üniversitesi, 2020)
Objective: The aim of this work is to synthesize 3-(alkylthio)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-4-
amines by the Milestone Flexi Wave microwave synthesis system and to prove structure synthesized compounds.
Material ...
Applications of miniaturized and portable near infrared (nir), fourier transform infrared (ft-ir) and raman spectrometers for the inspection and control of pharmaceutical products
(Ankara Üniversitesi, 2020)
Objective: In this review, the wide range of different applications of portable and miniaturized Fourier
transform infrared (FT-IR), near-infrared (NIR), and Raman spectrometers for quality control, assessment and
inspection ...
Novel tacrine and hesperetin analogues: design, molecular docking and in silico adme studies to identify potential acetyl choline esterase inhibitors for alzheimer’s disease
(Ankara Üniversitesi, 2020)
Objective: Present investigationis aimed to design and identify new potential molecules to treat Alzheimer’s
disease from the Tacrine and Hesperetin structures via molecular modification. Acetyl cholinesterase (AChE)
enzyme ...
Evaluation on gallic acid, egcg contents and antiradical activity of green tea and black tea extracts
(Ankara Üniversitesi, 2020)
Objective: Tea is very well known and consumed beverage worldwide also cultivated widely. It is one of
phytonutrients that has a protective role associated with its antioxidant activity. The aim of this article is to
study ...
