Özbek, LeventTemuçin, ÇağrıCengiz, BülentÖztürk, Fikri2021-11-302021-11-302019-06-30http://hdl.handle.net/20.500.12575/76511In this study, the emergences of postsynaptic action potentials are investigated using simulation study which is depended on the statistical model of acetylcholine (Ach) quantal release theory at motor end-plate. It is supposed that the end-plate potentials (EPP) are sum of miniature end-plate potentials (MEPP) which are released as quantal and random in number (N). By the hypothesis that N number has a Poisson and MEPPs have a Gaussian distribution, EPPs are obtained by simulating distributions parameters. Our study suggests that the simulation of the EPPs are a convenient tool in understanding both physiological process of synaptic transmission and pathological process of neuromuscular junction.enSynaptic transmissionEPPMEPPArticle69124322618-6462